Development of simple Covid-19 serological tools and targeted serosurvey of at-risk individuals (COVID-19 Serosurvey project)
- Funded by Institut Pasteur International Network (IPIN)
- Total publications:0 publications
Grant number: COVID-19 Serosurvey
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Key facts
Disease
COVID-19Start & end year
N/AFunder
Institut Pasteur International Network (IPIN)Research Location
CambodiaLead Research Institution
N/AResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnosticsResearch Subcategory
DiagnosticsSpecial Interest Tags
N/AStudy Type
Non-ClinicalClinical Trial Details
Not applicableBroad Policy Alignment
PendingAge Group
UnspecifiedVulnerable Population
UnspecifiedOccupations of Interest
Farmers, Other
Abstract
Aim: to develop simple serological tools that can be used to establish three tests: an enzyme-linked immunosorbent assay (ELISA), an immunofluorescence assay (IFA) and multiplex microsphere-based immunoassays (MIAs - capable of detecting several targets). This research will pave the way for the serological investigation of at-risk individuals such as those working at animal markets, farmers exposed to bat guano (used as a natural fertilizer) and those living in rural villages in Cambodia. Biological samples are available at the Institut Pasteur du Cambodge because of previous and current research conducted by the Virology Unit.SARS-CoV-2 diagnosis has hitherto been based on molecular biology methods (RT-PCR). Serological surveys, especially in at-risk individuals, will be a vital tool in improving our understanding of the epidemiology of the novel virus.