Return to homepagePandemic Pact

Australasian COVID-19 Trial (ASCOT)

  • Funded by Health Research Council of New Zealand
  • Total publications:0 publications

Grant number: unknown

Grant search

Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $467,328.93

  • Funder

    Health Research Council of New Zealand

  • Principal Investigator

    Susan Morpeth

  • Research Location

    New Zealand, Australia

  • Lead Research Institution

    Middlemore Clinical Trials

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Supportive care, processes of care and management

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Randomized Controlled Trial

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

ASCOT is an open label randomised controlled trial of unproven treatments for pandemic coronavirus infection among people unwell enough to need admission to hospital, but not so unwell that they need intensive care. Consenting participants will be randomised to either lopinavir-ritonavir (an anti-viral used to treat HIV), hydroxychloroquine (used in autoimmune diseases), both of these agents in combination, or the current standard of care. The study will be carried out at multiple sites across Australia and New Zealand. We will see whether either or both of these potential treatments will reduce the risk of needing intensive care or risk of death from pandemic coronavirus infection.