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  • Funded by UK Research and Innovation (UKRI)
  • Total publications:9 publications

Grant number: EP/N018591/1

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2016
    2021

  • Known Financial Commitments (USD)

    $599,331.83

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Chris Woods

  • Research Location

    United Kingdom

  • Lead Research Institution

    University of Bristol

  • Research Priority Alignment

    N/A

  • Research Category

    N/A

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This project aims to develop sustainable RSE career pathways and funding at Bristol. This will support the growth of a sustainable team of RSEs at the University. Software development projects that will be supported include; the building of code to interface real biological cells with virtual simulated cells, so to support the rapid design of new biomanufacturing control processes; the development of code to more quickly model the behaviour of electrons in novel materials, to support the design of new fuel cells and batteries; code to improve our understanding of glass-like matter, so to help design new materials with exciting new properties; software to support modelling of the quantum interaction between laser light and microscopic nanoparticles, to support the design of optical tweezers and new optically driven nanomachines; and code to design new medicinal drugs and to understand why existing treatments are no longer working, thereby supporting the development of 21st century medicine.

Publicationslinked via Europe PMC

Last Updated:2 hours ago

View all publications at Europe PMC

Exploration of the structural requirements of Aurora Kinase B inhibitors by a combined QSAR, modelling and molecular simulation approach.

Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology.

Sharing Data from Molecular Simulations.

A General Mechanism for Signal Propagation in the Nicotinic Acetylcholine Receptor Family.

Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display.

Visualizing protein-ligand binding with chemical energy-wise decomposition (CHEWD): application to ligand binding in the kallikrein-8 S1 Site.

A Multiscale Simulation Approach to Modeling Drug-Protein Binding Kinetics.

L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib.

Elucidation of Nonadditive Effects in Protein-Ligand Binding Energies: Thrombin as a Case Study.