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  • Funded by UK Research and Innovation (UKRI)
  • Total publications:9 publications

Grant number: EP/N018591/1

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A
    2021

  • Known Financial Commitments (USD)

    $599,331.83

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Chris Woods

  • Research Location

    United Kingdom

  • Lead Research Institution

    University of Bristol

  • Research Priority Alignment

    N/A

  • Research Category

    N/A

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This project aims to develop sustainable RSE career pathways and funding at Bristol. This will support the growth of a sustainable team of RSEs at the University. Software development projects that will be supported include; the building of code to interface real biological cells with virtual simulated cells, so to support the rapid design of new biomanufacturing control processes; the development of code to more quickly model the behaviour of electrons in novel materials, to support the design of new fuel cells and batteries; code to improve our understanding of glass-like matter, so to help design new materials with exciting new properties; software to support modelling of the quantum interaction between laser light and microscopic nanoparticles, to support the design of optical tweezers and new optically driven nanomachines; and code to design new medicinal drugs and to understand why existing treatments are no longer working, thereby supporting the development of 21st century medicine.

9 Publications linked via Europe PMC

Last Updated:7 days ago

View all publications at Europe PMC

Exploration of the structural requirements of Aurora Kinase B inhibitors by a combined QSAR, modelling and molecular simulation approach.

Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology.

Sharing Data from Molecular Simulations.

Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display.

A General Mechanism for Signal Propagation in the Nicotinic Acetylcholine Receptor Family.

Visualizing protein-ligand binding with chemical energy-wise decomposition (CHEWD): application to ligand binding in the kallikrein-8 S1 Site.

A Multiscale Simulation Approach to Modeling Drug-Protein Binding Kinetics.

L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib.

Elucidation of Nonadditive Effects in Protein-Ligand Binding Energies: Thrombin as a Case Study.