Disease Pathogenesis | Pandemic PACT Tracker

Key facts

Disease
COVID-19
start year
-99
Known Financial Commitments (USD)
$3,287,800.49
Funder
UK Research and Innovation (UKRI)
Principal Investigator
Prof. JA Hammond
Research Location
United Kingdom
Lead Research Institution
The Pirbright Institute
Research Priority Alignment
N/A

Research Category
N/A
Research Subcategory
N/A
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified

Abstract

PI: Enhanced host responses for disease control: a BBSRC Strategic Programme

Publicationslinked via Europe PMC

Last Updated:44 minutes ago

View all publications at Europe PMC

Recombinant infectious bronchitis virus containing mutations in non-structural proteins 10, 14, 15, and 16 and within the macrodomain provides complete protection against homologous challenge.

A broadly reactive ultralong bovine antibody that can determine the integrity of foot-and-mouth disease virus capsids.

Risk factors for severe COVID-19 disease increase SARS-CoV-2 infectivity of endothelial cells and pericytes.

The spike protein of the apathogenic Beaudette strain of avian coronavirus can elicit a protective immune response against a virulent M41 challenge.

The Influenza A Virus Replication Cycle: A Comprehensive Review.

Quantifying the relationship between within-host dynamics and transmission for viral diseases of livestock.

IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics.

A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein.

Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors.