Disease Pathogenesis | Pandemic PACT Tracker

Key facts

Disease
COVID-19
Start & end year
N/A
Known Financial Commitments (USD)
$3,287,800.49
Funder
UK Research and Innovation (UKRI)
Principal Investigator
Prof. JA Hammond
Research Location
United Kingdom
Lead Research Institution
The Pirbright Institute
Research Priority Alignment
N/A

Research Category
N/A
Research Subcategory
N/A
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified

Abstract

PI: Enhanced host responses for disease control: a BBSRC Strategic Programme

190 Publications linked via Europe PMC

Last Updated:10 hours ago

View all publications at Europe PMC

Pericyte dysfunction alone may be insufficient to drive tick-borne orthoflavivirus non-structural protein 1-mediated microvascular permeability.

Innate immune reprogramming of chicken macrophages by sodium butyrate enhances reactive oxygen species-mediated antimicrobial responses in vitro.

Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific immune response after vaccination and challenge.

Cattle antibodies identify a cross-serotype broadly neutralising foot-and-mouth disease virus epitope.

Authors
Bonnet-Di Placido M, Duyvesteyn HME, Steyn AW, Hay AL, Porta C, Valdez KR, Lokhman E, Crossley S, Hanson K, Mwangi WN, Munir D, Perez-Martin E, Knowles NJ, Burman A, Yassin AA, Asfor A, Faralla C, Lam KJ, McComb R, Leifeld C, Pietersz K, King DP, van den Born E, Duncan SK, Charleston B, Fry EE, Ren J, Stuart DI, Hammond JA.
Publish Year
2026
Journal
NPJ vaccines
DOI
10.1038/s41541-026-01427-7

View at Europe PMC

Genomic analysis of putative hybrids between Potamochoerus spp. and domestic pigs from sympatric areas in West Africa and Madagascar.

Evaluating how infectious bursal disease virus (IBDV) infection influences influenza H3N8 challenge in chickens.

Pericyte dysfunction alone may be insufficient to drive tick-borne orthoflavivirus NS1-mediated microvascular permeability

Butyrate Enhances Antimicrobial Defence in Chicken Macrophages Through Reactive Oxygen Species Generation and Autophagy Activation.

Recombinant infectious bronchitis virus containing mutations in non-structural proteins 10, 14, 15, and 16 and within the macrodomain provides complete protection against homologous challenge.