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THEME 3 - COVID-19 molecular mechanisms and target identification

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-254

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Key facts

  • Disease

    COVID-19

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    N/A

  • Research Location

    United Kingdom

  • Lead Research Institution

    Francis Crick Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Our COVID-19 research strategy takes a comprehensive and collaborative approach to research under five key themes. Theme 3 is "Molecular mechanisms and target identification", how does the virus infect our cells and how can we use this information to identify potential treatments? Aiming to define and validate tractable antiviral drug targets and providing assays for others working in this field. The focus will be on 1. Virus-cell surface interactions which could translate into diagnostic tests for neutralising antibodies, 2. Viral entry, generating mutants with fluorescent markers to understand the viral lifecycle and 3. Virus replication, transcription and translation for mechanistic insights.