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THEME 4 - Clinical epidemiology and management in healthy subjects

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-255

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Key facts

  • Disease

    COVID-19

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Pending

  • Research Location

    United Kingdom

  • Lead Research Institution

    Francis Crick Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease transmission dynamics

  • Special Interest Tags

    N/A

  • Study Subject

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Our COVID-19 research strategy takes a comprehensive and collaborative approach to research under five key themes. Theme 4 is "Clinical epidemiology and clinical management in well subjects", how is coronavirus transmitted and is it evolving? Can lifestyle and ethnicity make the disease more severe? Applying molecular viral typing to trace the transmission of SARS-CoV-2 viral strains and correlating data on infection with individual parameters of susceptibility in order to better understand the factors that define viral spread in different settings. Focus of work will be on 1. Viral transmission and evolution, 2. Influence of the host immune response on disease outcome and 3. Mechanisms of viral-induced organ damage and death.