UKRI Innovation Fellowship: Next Generation Endoscopes. Multifunctional endoscopic pharmaceutical treatments for COVID-19

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:12 publications

Grant number: EP/S001123/1

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Key facts

  • Disease

    COVID-19
  • Known Financial Commitments (USD)

    $387,803.17
  • Funder

    UK Research and Innovation (UKRI)
  • Principle Investigator

    Pending
  • Research Location

    United Kingdom, Europe
  • Lead Research Institution

    University of Bath
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    Gender

  • Study Subject

    Not applicable

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

As part of these COVID-19 related activities the applicant is seeking urgent funding to rapidly push and translate their endoscopic device (Panoptes) into COVID-19 focussed clinical studies. It will be used in conjunction with optical imaging platforms developed at the University of Edinburgh. Together these will enable them to (i) understand how COVID-19 is causing lung damage and respiratory failure and (ii) rapidly screen and monitor promising pharmaceutical assets which are either repurposed or at an advanced stage with feasibility studies in patients. They are specifically seeking funds to expedite the Panoptes device through regulatory approval and improve, streamline and upscale the Panoptes manufacturing process. This will enable them to produce devices for clinical use and to carry out research using direct clinical feedback from initial interventions to further develop the Panoptes platform thus contributing a vital role in the research of the broader consortium into COVID-19.

Publicationslinked via Europe PMC

Last Updated:39 minutes ago

View all publications at Europe PMC

Computational Fluorescence Suppression in Shifted Excitation Raman Spectroscopy.

Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs.

Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time-resolved fluorescence spectroscopy.

Stack, seal, evacuate, draw: a method for drawing hollow-core fiber stacks under positive and negative pressure.

Micro-Lensed Negative-Curvature Fibre Probe for Raman Spectroscopy.

Sub millimetre flexible fibre probe for background and fluorescence free Raman spectroscopy.

Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies.

A hydrogel-based optical fibre fluorescent pH sensor for observing lung tumor tissue acidity.

Core crosstalk in ordered imaging fiber bundles.