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scCoV2-Einzelsequenzierung von SARS-CoV2-infizierten Zellen

  • Funded by Federal Ministry of Research, Technology and Space (BMFTR)
  • Total publications:1 publications

Grant number: 01KI20269

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2021
  • Known Financial Commitments (USD)

    $54,122.39
  • Funder

    Federal Ministry of Research, Technology and Space (BMFTR)
  • Principal Investigator

    Prof. Markus Landthaler
  • Research Location

    Germany
  • Lead Research Institution

    Max-Delbrück-Centrum für Molekulare Medizin, Berlin
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

discovery - This is a basic scientific research project on SARS-CoV-2. The aim of the project is to investigate in detail the mutual influences between the viruses and the metabolism of human host cells in SARS-CoV-2 infection. Specifically, the ribonucleic acids (RNA) of individual cells from cell lines infected with SARS-CoV-2 are to be examined (sequenced) and analyzed in detail in the project. Based on the findings, cell culture models are to be developed that can be used for further questions on SARS-CoV-2 infections.

1 Publication linked via Europe PMC

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.