Profile-Covid Rapid diagnostic profiling of SARS-CoV-2 in the context of persistent immune activation in sub-Saharan Africa

  • Funded by European & Developing Countries Clinical Trials Partnership (EDCTP)
  • Total publications:1 publications

Grant number: RIA2020EF-2905

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Key facts

  • Disease

    COVID-19
  • start year

    2020
  • Known Financial Commitments (USD)

    $559,529.6
  • Funder

    European & Developing Countries Clinical Trials Partnership (EDCTP)
  • Principal Investigator

    Pending
  • Research Location

    Ethiopia, Ghana
  • Lead Research Institution

    Mekelle University
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Subject

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The Profile-Cov project (RIA2020EF-2905) aims to evaluate the profile of the immune response of the Ethiopian population and will examine its relationship with the noted low CD4+ T-cell count and underlying immune activation status among patients with COVID-19 and will compare the results with data collected in Europe.

Publicationslinked via Europe PMC

Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy.