COVER

Grant number: 221556/Z/20/Z

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2020
  • Known Financial Commitments (USD)

    $245,798
  • Funder

    Wellcome Trust
  • Principal Investigator

    Prof. Ruth Faden
  • Research Location

    United States of America, Nigeria
  • Lead Research Institution

    Johns Hopkins University
  • Research Priority Alignment

    N/A
  • Research Category

    Research to inform ethical issues

  • Research Subcategory

    Research to inform ethical issues in Research

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Adults (18 and older)

  • Vulnerable Population

    Pregnant women

  • Occupations of Interest

    Unspecified

Abstract

With the rapid development of candidate vaccines for COVID-19, this project will identify and provide guidance on a range ethical issues arising in the development and deployment of COVID-19 vaccines. Over the next six months, the COVER project will concentrate on the ethics of vaccine research and development-including phase 3 trial design and equitable inclusion of special populations in the research agenda, with a particular focus on pregnant women as well as population groups that have or likely will experience disproportionate burden from COVID-19. This project will also conduct formative landscaping work on the ethical challenges and tradeoffs in the allocation and deployment of vaccines, both globally and within nations. This work will lay the groundwork for normative guidance and mathematical models to best inform policymaking once efficacious vaccines become available for wider use, with explicit consideration and assessment of how various approaches will not only impact the trajectory of the COVID-19 pandemic overall, but also how the benefits of vaccination will be fairly distributed across different population subgroups. In addition, the COVER project will begin to address ethical issues of COVID-19 vaccine development and deployment specific to Africa, with a concentrated body of work in Nigeria.

Publicationslinked via Europe PMC

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Global disparities in public health guidance for the use of COVID-19 vaccines in pregnancy.

Advancing research in pregnancy during COVID-19: Missed opportunities and momentum in the US.