Return to homepagePandemic Pact

A public resource of humanized mice to speed up studies of SARS-CoV-2 infections]

  • Funded by Fondation pour la Recherche Médicale
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $237,168

  • Funder

    Fondation pour la Recherche Médicale

  • Principal Investigator

    Bernard MALISSEN

  • Research Location

    France

  • Lead Research Institution

    Directeur du Centre d'Immunophénomique à Marseille

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This project aims to very quickly develop 5 humanized mouse models whose cells have on their surface a protein similar to that to which the Sars-CoV-2 virus binds when it infects human cells. Vaccines and antiviral therapies can then be tested on these rodents. These animal models will also help to deepen our knowledge of infectious mechanisms.