identification of monogenic immunity defects responsible for severe forms of COVID-19 in previously healthy patients]

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $181,889.8
  • Funder

    Other funders (France)
  • Principal Investigator

    Jean-Laurent CASANOVA
  • Research Location

    France
  • Lead Research Institution

    Institut Imagine, Paris
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The GENCOVID project aims to determine whether the severe forms of Covid-19 encountered in young and healthy people could be linked to monogenic mutations (an error in a single gene in an individual), present from birth and affecting the immunity. Identifying the genes involved could shed light on the mechanisms at work in these severe forms