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Lung cell senescence as a target to control COVID-19

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    François TROTTEIN

  • Research Location

    France

  • Lead Research Institution

    Institut Pasteur / Lille

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The SENOCOVID project coordinated by François Trottein (Institut Pasteur / Lille) focuses on pulmonary cell senescence as a target for controlling Covid-19. It will focus on quantifying the accumulation of senescent cells during SARS-CoV-2 infection, determining the nature of senescent cells and the molecular signatures of this senescence and analyzing the impact of a pre-existing senescence and / or induced on viral replication and pulmonary lesions, using two complementary experimental models.