COVID-NURSE. The development, testing and evaluation of a COVID-19 fundamental nursing care protocol: a randomised controlled trial

  • Funded by Department of Health and Social Care / National Institute for Health and Care Research (DHSC-NIHR), UK Research and Innovation (UKRI)
  • Total publications:6 publications

Grant number: MR/V02776X/1

Grant search

Key facts

  • Disease

  • Start & end year

  • Known Financial Commitments (USD)

  • Funder

    Department of Health and Social Care / National Institute for Health and Care Research (DHSC-NIHR), UK Research and Innovation (UKRI)
  • Principle Investigator

  • Research Location

    United Kingdom, Europe
  • Lead Research Institution

    University of Exeter
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Clinical trials for disease management

  • Special Interest Tags


  • Study Subject


  • Clinical Trial Details

    Randomized Controlled Trial

  • Broad Policy Alignment


  • Age Group


  • Vulnerable Population


  • Occupations of Interest



Background: nursing care is a key determinant of patient experience and correlated withsafety, clinical effectiveness, care quality, treatment outcomes and reduced overall serviceuse. No evidence-based nursing protocols exist to address the unique challenges ofnursing hospitalised patients with the SARS-CoV-2 virus.Aim: to co-create and evaluate the impact on patient experience, care quality, functionalability, treatment outcomes and costs of a nursing care protocol specifically addressingthe fundamental care requirements of hospitalised patients with the SARS-CoV-2 virus notinvasively ventilated.Methods: 2-stage mixed-methods programme, following revised 2020 complexinterventions guidance, of: 1) rapid-review, survey, co-creation consensus development ofa nursing protocol; 2) rapid-cycle cluster randomised controlled trial with embeddedprocess and economic evaluations.Deliverables:1.Fundamental nursing care protocol for hospitalised patients with the SARS-CoV-2 virusnot invasively ventilated, with proven effectiveness on patient experience, care quality,functional ability and treatment outcomes within 9 months of project inception.2.Feasible, acceptable and 'implementation-optimised' protocol for widespreadimplementation, through co-creation and changes implemented during rapid cycle trialwaves.3.Adaptable protocol designed to be generalisable for environments such as care homes,patients with other conditions requiring isolation and to global health systems viaknowledge gained in a process analysis of intervention fidelity, mechanisms, contextualfactors and implementation.4.Guidelines, education materials and strategies accessible via Health Education England,the Open University's FutureLearn web platform, and experienced NHS sites acting astraining hubs for other health Trusts/care homes/global health systems.

Publicationslinked via Europe PMC

Last Updated:39 minutes ago

View all publications at Europe PMC

Evaluation of a COVID-19 fundamental nursing care guideline versus usual care: The COVID-NURSE cluster randomized controlled trial.

Nurses' strategies for overcoming barriers to fundamental nursing care in patients with COVID-19 caused by infection with the SARS-COV-2 virus: Results from the 'COVID-NURSE' survey.

Fundamental nursing care in patients with the SARS-CoV-2 virus: results from the 'COVID-NURSE' mixed methods survey into nurses' experiences of missed care and barriers to care.

Impact of COVID-19 and other infectious conditions requiring isolation on the provision of and adaptations to fundamental nursing care in hospital in terms of overall patient experience, care quality, functional ability, and treatment outcomes: systematic review.

COVID-NURSE: evaluation of a fundamental nursing care protocol compared with care as usual on experience of care for noninvasively ventilated patients in hospital with the SARS-CoV-2 virus-protocol for a cluster randomised controlled trial.

Increasing recruitment into covid-19 trials: fund nursing trials.