A Rapid Research Platform to Inform Prevention and Improve the Clinical Management of COVID-19 Illness for Priority Older Adult Groups: The Ontario Multi-Regional Hospital Coronavirus Registry (COREG)

  • Funded by Canadian Institutes of Health Research (CIHR)
  • Total publications:5 publications

Grant number: 172754

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2020
  • Known Financial Commitments (USD)

    $346,586.25
  • Funder

    Canadian Institutes of Health Research (CIHR)
  • Principle Investigator

    Pending
  • Research Location

    Canada, Americas
  • Lead Research Institution

    McMaster University Health Research Methods, Evidence, and Impact
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease susceptibility

  • Special Interest Tags

    Gender

  • Study Subject

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Older adults (65 and older)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Older adults are the more vulnerable to developing COVID-19 and its complications, particularly home care and retirement home residents. Older persons are also less likely to regain full functional and health recovery after a COVID-19 illness. We have little information on why some people develop severe COVID-19; and how COVID-19 may affect older adults in Canada. There is no information on the medium- and long-term outcomes in survivors and how we can improve their recovery rate and prevent health and functional loss. Rapid large-scale Canadian data platforms, with detailed information on patients with COVID-19 and their clinical course, are needed to address these questions and help plan strategies that can limit the spread and the impact of COVID-19 in older adults now and in the future. We are launching the Ontario Multi-Regional Hospital Coronavirus Registry (COREG), a platform that collects detailed case data on confirmed COVID-19 inpatients, and outpatients, in collaboration with the World Health Organization. We will address these critical gaps, with linkage to provincial data to identify risk factors for severe COVID-19 and death in older adults in the general population, home care, and retirement homes in Ontario. The COREG platform will document the clinical course to 9 months, to study the functional recovery and the need for targeted rehabilitative treatments. COREG will provide rapid high-quality evidence to improve the prevention and clinical management of COVID-19 for older adults in Canada, and internationally. COREG will also provide researchers and partners with complete and in-depth regional and individual-level clinical data on COVID-19 to inform rapid decision-making and projections, sub-studies, extensions, and linkage for all affected populations.

Publicationslinked via Europe PMC

Last Updated:39 minutes ago

View all publications at Europe PMC

Hospitalised COVID-19 outcomes are predicted by hypoxaemia and pneumonia phenotype irrespective of the timing of their emergence.

Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort study.

How "green" can religions be? Tensions about religious environmentalism.

External validation of the 4C mortality score among COVID-19 patients admitted to hospital in Ontario, Canada: a retrospective study.

Inflammatory biomarkers as independent prognosticators of 28-day mortality for COVID-19 patients admitted to general medicine or ICU wards: a retrospective cohort study.