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COVID-19 and the innate immune response: phagocytic dysfunction in SARSCoV2 infection

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    Margarita Hurtado-Nedelec

  • Research Location

    France

  • Lead Research Institution

    Centre de Recherche sur l'Inflammation - Hôpital Bichat

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The COVINNATE project, coordinated by Margarita Hurtado-Nedelec (U 1149 - Center for Research on Inflammation - Bichat Hospital), concerns the study of the involvement of phagocytes in the pathogenesis and immune response of Covid-19, to different stages of the disease. He will analyze the main molecular effectors and functions of the innate immune response in phagocytes during disease, as well as their correlation with inflammatory markers and adverse clinical outcomes.