Transdermal oxygen delivery to increase systemic oxygen supply for COVID-19 patients having no access to lung ventilators or patients where lung ventilators are not sufficient

Grant number: Unknown

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Key facts

  • Disease

    COVID-19
  • start year

    2020
  • Funder

    Volkswagen Stiftung
  • Principal Investigator

    Profs Drs Lars Kaestner, Anna Bogdanova, Matthias Laschke
  • Research Location

    Germany
  • Lead Research Institution

    Universität des Saarlandes Medizinische Fakultät Theoretische Medizin und Biowissenschaften Homburg/Saar Universität Zürich Vetsuisse Fakultät Institut für Veterinärphysiologie Zürich Schweiz
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Supportive care, processes of care and management

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The goal of the project "Transdermal oxygen delivery to increase systemic oxygen supply for COVID-19 patients having no access to lung ventilators or patients where lung ventilators are not sufficient" is to test whether oxygen supply through the skin treated with gels containing oxygen-concentrating fluorocarbons may result in better oxygenation of blood under conditions of poor oxygen absorption through the lungs. A successful proof of principle may open the possibility to supplement part of the oxygen to the body by way of transcutaneous delivery for patients on ventilation due to atypical pneumonia, such as Covid-19 infected patients, for which ventilation with pure oxygen is of little help due to an increase diffusion distance emerging during the inflammation.

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