Coronavirus interactions in drug discovery - optimization and implementation / Consortium: Covidd

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2022
  • Known Financial Commitments (USD)

    $1,632,878.1
  • Funder

    Academy of Finland
  • Principal Investigator

    Markku Varjosalo
  • Research Location

    Finland
  • Lead Research Institution

    University of Helsinki
  • Research Priority Alignment

    N/A
  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Prophylactic use of treatments

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Last November infections of a new kind of coronavirus were announced but no one could have then anticipated how large impact this new virus (SARS-CoV-2) would cause globally only few week after finding it. Now this SARS-CoV-2 has spread around almost every place on Earth including Finland. In this project a consortium of four groups from University of Helsinki and University of Eastern Finland plan to tackle the task in identifying molecules (drugs) that would interfere replication of the virus. Members of the consortia coverer different disciplines from virology to protein-protein interaction and structural biology ranging until drug discovery. We are planning to use a multiplicinary approach to test existing drugs that have already been allowed to be used in humans. We are testing which drugs or combination of drugs against human proteins would inhibit or slow down replication of the virus. This is the fastest way to get drugs against this virus.