Impact of Marijuana Legalization: Comparison of Two Longitudinal Twin Cohorts
- Funded by National Institutes of Health (NIH)
- Total publications:0 publications
Grant number: unknown
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Key facts
Disease
COVID-19Start & end year
20172022Known Financial Commitments (USD)
$154,303Funder
National Institutes of Health (NIH)Principal Investigator
CHRISTIAN J HOPFERResearch Location
United States of AmericaLead Research Institution
UNIVERSITY OF COLORADO DENVERResearch Priority Alignment
N/A
Research Category
Secondary impacts of disease, response & control measures
Research Subcategory
Indirect health impacts
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Drug users
Occupations of Interest
Unspecified
Abstract
This supplemental grant proposes to add questions to extend the aims of the parent project by collectingadditional data related to COVID-19 including financial hardships, social/interpersonal problems, stress, mentalhealth, and substance use changes. Data will also be collected on whether participants are essential workers,were exposed to COVID-19, or have been diagnosed with COVID-19.Parent grant Aim 1: Effect of RML on substance use/misuse, mental health, & psychosocial functionAim 1 extended: Effect of COVID-19 pandemic and RML on substance use/misuse, mental health &psychosocial function.We will test the hypothesis that access to RML increases the likelihood that the stress and disruptionassociated with COVID-19 will lead to increased marijuana use and abuse. Relatedly, we will test the extent towhich increased marijuana use, related to RML and stress/disruptions from COVID-19, is accompanied byincreases in other substance use, mental health disorders, or psychosocial dysfunction.Parent grant Aim 2: Individual differences in the effect of RMLAim 2 extended: Examine individual differences in the effect of COVID-19 pandemic and RML.Examine individual differences in the effects of COVID-19 and legalization by leveraging parallel multi-wavelongitudinal twin studies in CO and MN, which both began collecting substance use, psychopathology, andpsychosocial function during the twins' adolescence. This supplemental assessment will allow us to: a) identifyhow COVID-19 differentially impacts individuals depending on legalization and prior exposure to marijuana; b)examine how individuals differ in their vulnerability and resilience to the effects COVID-19, in the context oflegalization, based on their individual level of risk (e.g., prior diagnosis of anxiety or depression); and c)examine if there are differential associations between COVID-19 and substance use/dependence, mentalhealth, and psychosocial problems depending on legalization status and gender.