Impact of Marijuana Legalization: Comparison of Two Longitudinal Twin Cohorts

  • Funded by National Institutes of Health (NIH)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

  • Start & end year

  • Known Financial Commitments (USD)

  • Funder

    National Institutes of Health (NIH)
  • Principle Investigator

  • Research Location

    United States of America, Americas
  • Lead Research Institution

  • Research Category

    Secondary impacts of disease, response & control measures

  • Research Subcategory

    Indirect health impacts

  • Special Interest Tags


  • Study Subject


  • Clinical Trial Details


  • Broad Policy Alignment


  • Age Group


  • Vulnerable Population

    Drug users

  • Occupations of Interest



This supplemental grant proposes to add questions to extend the aims of the parent project by collectingadditional data related to COVID-19 including financial hardships, social/interpersonal problems, stress, mentalhealth, and substance use changes. Data will also be collected on whether participants are essential workers,were exposed to COVID-19, or have been diagnosed with COVID-19.Parent grant Aim 1: Effect of RML on substance use/misuse, mental health, & psychosocial functionAim 1 extended: Effect of COVID-19 pandemic and RML on substance use/misuse, mental health &psychosocial function.We will test the hypothesis that access to RML increases the likelihood that the stress and disruptionassociated with COVID-19 will lead to increased marijuana use and abuse. Relatedly, we will test the extent towhich increased marijuana use, related to RML and stress/disruptions from COVID-19, is accompanied byincreases in other substance use, mental health disorders, or psychosocial dysfunction.Parent grant Aim 2: Individual differences in the effect of RMLAim 2 extended: Examine individual differences in the effect of COVID-19 pandemic and RML.Examine individual differences in the effects of COVID-19 and legalization by leveraging parallel multi-wavelongitudinal twin studies in CO and MN, which both began collecting substance use, psychopathology, andpsychosocial function during the twins' adolescence. This supplemental assessment will allow us to: a) identifyhow COVID-19 differentially impacts individuals depending on legalization and prior exposure to marijuana; b)examine how individuals differ in their vulnerability and resilience to the effects COVID-19, in the context oflegalization, based on their individual level of risk (e.g., prior diagnosis of anxiety or depression); and c)examine if there are differential associations between COVID-19 and substance use/dependence, mentalhealth, and psychosocial problems depending on legalization status and gender.