COVID-19 and ischemic stroke - How to tame a dozing monster

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.043E+13

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Key facts

  • Disease

  • Start & end year

  • Known Financial Commitments (USD)

  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principle Investigator

  • Research Location

    Netherlands, Europe
  • Lead Research Institution

    Leiden University Medical Center
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags


  • Study Subject


  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment


  • Age Group


  • Vulnerable Population


  • Occupations of Interest



Project description Patients with COVID-19 pneumonia, especially when admitted to intensive care, may develop thrombotic complications that may contribute to a more serious course of COVID-19 pneumonia. Pulmonary embolism (clot in the lung) is the most common complication, but stroke can also occur. The hypothesis in this study is that these strokes may be caused by coagulation activation and inflammation of the arteries, or that they are the result of a blood clot entering the brain vessels from the leg or pelvic vessels through an open connection between the right and left sides of the heart. ends up. Research and expected outcomes In three work packages, knowledge is obtained about: an accurate estimate of the occurrence of ischemic stroke in COVID-19 IC patients. the causes and consequences of strokes based on imaging studies and lab tests. the optimal prevention of strokes by examining the effect of different treatments.