WikiPathways as a platform for COVID-19 pathway models. Identification of underlying mechanisms explaining differences in host immune response, disease severity and detection of mechanisms for targeted (drug) treatment

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.043E+13

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2022
  • Known Financial Commitments (USD)

    $470,997.11
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    Dr. M Kutmon
  • Research Location

    Netherlands
  • Lead Research Institution

    Maastricht University Medical Center+ǨǨ Ǩ
  • Research Priority Alignment

    N/A
  • Research Category

    Health Systems Research

  • Research Subcategory

    Health information systems

  • Special Interest Tags

    Data Management and Data Sharing

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Project description WikiPathways is a world-renowned and established knowledge platform, founded and maintained by Maastricht University. The platform makes molecular pathway models accessible to researchers, keeps its pathway collection up-to-date and supports the process of drug development for the different phases of COVID-19. Research The research has three aspects to help fight COVID-19 and future outbreaks: Extension of WikiPathways as a source for COVID-19 pathway models. This is done by sharing models and information and collaborating with all COVID-19 studies. Improvement of software to better describe virus-human interactions within relevant COVID-19 molecular processes so that computers can use them. The development of analysis procedures using the constant influx of knowledge, experiments and clinical data.