JAMVENT - a ventilator design constructed for rapid production

Until better means are found to treat the deadly sequelae of COVID-19, mechanical ventilation remains the difference between life and death for many patients. The unprecedented worldwide demand for ventilators is challenged by the complex design of existing ventilators, restricting accelerated production and amounting to high costs that limit the supply to resource-poor countries. Our ventilator, JAMVENT uses a relatively small number of simple components outside of hospital and existing ventilator supply chains, yet is able to perform the critical functions of ICU ventilators with three modes of operation: i) clinically-preferred Pressure Regulated Volume Control (PRVC); ii) maintenance of pressure during suctioning to remove secretions; and iii) spontaneous patient-triggered breathing mode, which is critical when weaning patients off ventilation. JAMVENT is compatible with both hospital gas supplies and the lower pressures provided by oxygen concentrators. With a component-robust design, low cost, streamlined manufacturing, and compliance with regulatory guidelines for emergency-use ventilators, JAMVENT is the ideal solution to the growing clinical need for critical respiratory equipment around the globe. We are requesting funds to further develop our laboratory prototype to aid our industrial partner, RPD International, in developing a large-scale manufacturing process and regulatory approval for emergency and long-term use internationally.