Real-time Federated Search of Host and Viral Genomes

Grant number: unknown

Grant search

Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $0
  • Funder

    Roche Holding AG (Roche)
  • Principal Investigator

    Marc Fiume
  • Research Location

    Canada
  • Lead Research Institution

    DNAstack
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen genomics, mutations and adaptations

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The risk factors for severe illness for COVID-19 are still being established. There is evidence that life-threatening immune responses (e.g. the cytokine storm syndrome) are mediated by the host human genome. At the same time, emerging data describes how multiple strains of the virus continue to evolve in different geographic areas, and experts around the world have called for a coordinated global approach involving ​genomic and epidemiological approaches. This project aims to develop technology to support fit-for-purpose real-time sharing, search, and analysis of viral and host genomes for COVID-19 and future disease outbreaks.