Controlling COVID19 through enhanced population surveillance and intervention (Con- COV): a platform approach

  • Funded by Department of Health and Social Care / National Institute for Health and Care Research (DHSC-NIHR), UK Research and Innovation (UKRI)
  • Total publications:67 publications

Grant number: MR/V028367/1

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2022
  • Known Financial Commitments (USD)

    $537,314.67
  • Funder

    Department of Health and Social Care / National Institute for Health and Care Research (DHSC-NIHR), UK Research and Innovation (UKRI)
  • Principle Investigator

    Pending
  • Research Location

    United Kingdom, Europe
  • Lead Research Institution

    Swansea University
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen genomics, mutations and adaptations

  • Special Interest Tags

    Gender

  • Study Subject

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Vulnerable populations unspecified

  • Occupations of Interest

    Social WorkersHealth PersonnelHospital personnelOther

Abstract

Background: COVID19 is a rapidly evolving complex issue that requires near real time data, analyses and multidisciplinary team science to devise, implement and evaluate a wide variety of inter- and cross-sectoral interventions in order to minimise population harm. Aims: to integrate multiple sources of data to produce timely and responsive analyses to: 1) provide detailed insight into the evolving pandemic in the general population, vulnerable groups and diverse settings (health care workers, social care workers, care homes and schools); 2) support and undertake evaluations of the effectiveness of adopted counter measures as these evolve; 3) rapidly inform policy and practice decision makers; and 4) communicate effectively with the general public. Methods: We will build on the existing total population 3.2 million Wales Multimorbidity Cohort funded by HDRUK/MRC to create the greatest in-depth COVID19 population study with data enhancements on vulnerable groups and settings, serology and viral genomics, scale the breadth and depth of disciplines involved and support embedded evaluations of countermeasures. Our multi-agency team includes individuals from Welsh Government, Public Health Wales, academics from multiple disciplines and members of the public. Deliverables: Reports on exposure risks, incidence and outcomes to Welsh Government COVID19 Technical Advisory Group (TAG) and onwards to SAGE; share models with multiple UK groups including SPI-M, triallists, and the Royal Society DELVE initiative; and provide evaluations of natural experiments in policy and practice. Timeline: We will report weekly to TAG and monthly to funders, recognising the time- sensitive requirements needed to inform evidence-based control and exit strategies.

Publicationslinked via Europe PMC

Last Updated:38 minutes ago

View all publications at Europe PMC

Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales.

Epilepsy and the risk of COVID-19-related hospitalization and death: A population study.

Risk of severe COVID-19 outcomes after autumn 2022 COVID-19 booster vaccinations: a pooled analysis of national prospective cohort studies involving 7.4 million adults in England, Northern Ireland, Scotland and Wales.

The cost of implementing the COVID-19 shielding policy in Wales.

Dimensions of equality in uptake of COVID-19 vaccination in Wales, UK: A multivariable linked data population analysis.

Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK.

Rationale for the shielding policy for clinically vulnerable people in the UK during the COVID-19 pandemic: a qualitative study.

Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005-2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals.

The impact of the COVID-19 pandemic on community prescription of opioid and antineuropathic analgesics for cancer patients in Wales, UK.