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Understanding and manipulating innate-like B cell mechanisms to prevent stroke associated Infection

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-045

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Dr. Barry McColl

  • Research Location

    United Kingdom

  • Lead Research Institution

    UK Dementia Research Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Individuals with multimorbidity, Other

  • Occupations of Interest

    Unspecified

Abstract

Amendment to an existing study - awaiting approval to add a COVID arm to MRC-funded stroke cohort that recently finished recruiting. This cohort has undergone deep immunophenotyping early after stroke to understand stroke-induced immune changes, infection risk, and associations with long-term outcome (including cognition). Project has potential implications for informing patient management prioritisation.