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Iron biology and COVID-19

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-266

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Professor Graham Ogg

  • Research Location

    United Kingdom

  • Lead Research Institution

    MRC Human Immunology Unit at the University of Oxford

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

A feature of patients with severe COVID-19 infection is anaemia and changed concentrations of iron in the bloodstream. We are investigating whether the altered iron levels and the anaemia might cause less efficient immune responses against the virus, allowing the infection to persist. If so, therapies aimed at correcting iron imbalances might improve the outcome of infection.