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DECIPHERING THE VIRUS INTERACTIONS WITH THE ENTRY RECEPTORS IN HUMAN CELLS, AND THEIR POTENTIAL INHIBITION (DSAC project)

  • Funded by Institut Pasteur International Network (IPIN)
  • Total publications:250 publications

Grant number: Unknown

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Key facts

  • Disease

    COVID-19

  • Funder

    Institut Pasteur International Network (IPIN)

  • Principal Investigator

    N/A

  • Research Location

    N/A

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Researchers will develop and employ a workflow that combines cryogenic light and electron microscopy imaging modalities with computational analysis and data mining to determine high-resolution in-situ structural images of the virus-spike interactions with cell receptors and with the antibodies that abrogate their cell entry. These studies will provide a blueprint for the design of vaccines and therapeutics.

Publicationslinked via Europe PMC

Last Updated:11 days ago

View all publications at Europe PMC

Effects of Hand-Rearing and Group Size on Chimpanzee (<i>Pan troglodytes</i>) Social Competence in Captivity.

Revisiting Spirituality in Physical Therapy Practice: Perceptions of US Practitioners.

Aflibercept for Wet Age-Related Macular Degeneration: A Prospective, Randomized Trial Comparing Treat-And-Extend and Fixed Bimonthly Dosing.

The Concentration and Duration of Lipopolysaccharide Stimulation Produce Different Cytokine Responses in an Ex Vivo Whole Blood Model in Horses.

History of Shrimp Farming and the Main Viral and Bacterial Diseases in Mexico.

Identification of Risk Factors in Patients with Recurrent Cystitis May Improve Individualized Management.

IS<i>Apl4</i>, a New IS<i>1595</i> Family Insertion Sequence Forming a Novel Pseudo-Compound Transposon That Confers Antimicrobial Multidrug Resistance in <i>Actinobacillus pleuropneumoniae</i>.

Delivering the Parenting for Lifelong Health Programme with Parents of Young Children in Wales.

Living with Dysphagia and Dysarthria: A Qualitative Exploration of the Perspectives of People with Motor Neuron Disease and Their Caregivers.