NEUROLOGICAL IMPLICATIONS OF SARS-COV-2 INFECTION - A TRANSVERSAL STUDY (Neurological project)
- Funded by Institut Pasteur International Network (IPIN)
- Total publications:239 publications
Grant number: Unknown
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Key facts
Disease
COVID-19Funder
Institut Pasteur International Network (IPIN)Principal Investigator
N/A
Research Location
N/ALead Research Institution
N/AResearch Priority Alignment
N/A
Research Category
Clinical characterisation and management
Research Subcategory
Disease pathogenesis
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
The infection of the nasal mucosa and the lungs by CoV-2 may spread to the CNS, including the brainstem, thereby playing a potential key role in the severe respiratory distress observed in COVID-19. Although several clinical observations support this hypothesis, the knowledge in this field is very limited. To fill this gap, we will investigate CoV-2 neuroinvasion in humans, animal models, and cell culture-based experimental models and decipher the molecular mechanisms involved. Results of this project will provide clues on whether targeting potential neurotropism of CoV-2 may be relevant approach for experimental therapeutics in Covid-19.
Publicationslinked via Europe PMC
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