URGENT DISCOVERY OF DRUG CANDIDATES THAT TARGET CORONAVIRUS SARS-COV-2 (DrugCandidates-SARS-CoV-2 project)

  • Funded by Institut Pasteur International Network (IPIN)
  • Total publications:250 publications

Grant number: Unknown

Grant search

Key facts

  • Disease

    COVID-19
  • Funder

    Institut Pasteur International Network (IPIN)
  • Principal Investigator

    N/A

  • Research Location

    N/A
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

rapidly provide drug candidates to treat victims of Covid-19. We will do this by applying our cutting-edge technologies and libraries to screen for viable active compounds that kill coronavirus. The strategy will employ phenotype screens (FPDD) that test for coronavirus inhibition using mouse (MHV-59) and human (OC43) virus as models for fast compound screening in cell culture. Direct-acting antivirals will also be sought via target-based screening (FBDD) as inhibitors of essential viral proteins of SARS-CoV-2.

Publicationslinked via Europe PMC

Last Updated:16 hours ago

View all publications at Europe PMC

Effects of Hand-Rearing and Group Size on Chimpanzee (<i>Pan troglodytes</i>) Social Competence in Captivity.

Revisiting Spirituality in Physical Therapy Practice: Perceptions of US Practitioners.

Aflibercept for Wet Age-Related Macular Degeneration: A Prospective, Randomized Trial Comparing Treat-And-Extend and Fixed Bimonthly Dosing.

The Concentration and Duration of Lipopolysaccharide Stimulation Produce Different Cytokine Responses in an Ex Vivo Whole Blood Model in Horses.

History of Shrimp Farming and the Main Viral and Bacterial Diseases in Mexico.

Identification of Risk Factors in Patients with Recurrent Cystitis May Improve Individualized Management.

IS<i>Apl4</i>, a New IS<i>1595</i> Family Insertion Sequence Forming a Novel Pseudo-Compound Transposon That Confers Antimicrobial Multidrug Resistance in <i>Actinobacillus pleuropneumoniae</i>.

Delivering the Parenting for Lifelong Health Programme with Parents of Young Children in Wales.

Living with Dysphagia and Dysarthria: A Qualitative Exploration of the Perspectives of People with Motor Neuron Disease and Their Caregivers.