SBIR Phase I: A new vaccine technology to engineer a potent and polarized immunity against COVID-19

  • Funded by National Science Foundation (NSF)
  • Total publications:0 publications

Grant number: 2031727

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2021
  • Known Financial Commitments (USD)

    $255,998
  • Funder

    National Science Foundation (NSF)
  • Principal Investigator

    Stephanie Deshayes
  • Research Location

    United States of America
  • Lead Research Institution

    Tempo Therapeutics
  • Research Priority Alignment

    N/A
  • Research Category

    Vaccines research, development and implementation

  • Research Subcategory

    Vaccine design and administration

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The broader impact of this Small Business Innovation Research (SBIR) Phase I project will advance a new vaccine delivery technology against new emerging pathogens such as that causing COVID-19. This project will develop a new process that can be rapidly manufactured with high affinity and precision-engineered immune responses. The technology is based on new materials that can be injected to help support the immune system.

This Small Business Innovation Research (SBIR) Phase I project will advance a novel vaccine delivery technology using flowable hyper-porous and synthetic materials. This new material technology can be easily injected subcutaneously or intramuscularly to deliver vaccine antigens. The material itself acts as a long-lasting antigen delivery vehicle, increasing antibody production and polarizing the immune system to maximize protective immunity against the delivered antigens. This project specifically focuses on development of this novel material to create multifactor immunity against the novel coronavirus (SARS-CoV-2) to protect against COVID-19.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.