Genetic risk factors that determine Covid-19 susceptibility and severity

Key facts

Disease
COVID-19
start year
2020
Known Financial Commitments (USD)
$0
Funder
NWO Netherlands
Principal Investigator
Prof dr LH Franke
Research Location
Netherlands
Lead Research Institution
Universitair Medisch Centrum Groningen
Research Priority Alignment
N/A

Research Category
Clinical characterisation and management
Research Subcategory
Prognostic factors for disease severity
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified

Abstract

It is mostly unclear why some people get severely ill due to a Covid-19 infection. We hypothesize this is partly due to genetic risk factors that determine both Covid-19 susceptibility and severity. In this project we will conduct a genome-wide association study in the Lifelines biobank, which has previously generated genotype data for 50,000 participants. We are sending out questionnaires to them, asking about Covid-19 related symptoms, permitting us to study the genetics of Covid-19 infection susceptibility and severity.

Publicationslinked via Europe PMC

Last Updated:5 hours ago

View all publications at Europe PMC

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