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Genetic risk factors that determine Covid-19 susceptibility and severity

Grant number: Unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020

  • Known Financial Commitments (USD)

    $0

  • Funder

    NWO Netherlands

  • Principal Investigator

    Prof dr LH Franke

  • Research Location

    Netherlands

  • Lead Research Institution

    Universitair Medisch Centrum Groningen

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

It is mostly unclear why some people get severely ill due to a Covid-19 infection. We hypothesize this is partly due to genetic risk factors that determine both Covid-19 susceptibility and severity. In this project we will conduct a genome-wide association study in the Lifelines biobank, which has previously generated genotype data for 50,000 participants. We are sending out questionnaires to them, asking about Covid-19 related symptoms, permitting us to study the genetics of Covid-19 infection susceptibility and severity.