Single cell molecular signatures in blood and tissues from mild and severe COVID19 patients
- Funded by Wellcome Trust
- Total publications:0 publications
Grant number: CV002
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Key facts
Disease
COVID-19Start & end year
20202020Funder
Wellcome TrustPrincipal Investigator
PendingResearch Location
United KingdomLead Research Institution
Wellcome Sanger InstituteResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Immunity
Special Interest Tags
N/A
Study Subject
Non-Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
Key questions: What immune pathways and cellular phenotypic states distinguish COVID-19 severity? How do immune cell populations in blood and lung relate in severe COVID-19? Aims: To uncover immune signatures underlying severe disease, revealing candidate immune pathways involved in pathogenesis, Identify candidate predictive biomarkers for larger scale studies, Rapidly provide robust in vivo evidence to guide therapeutic intervention