Investigating longitudinal immune responses to SARSCoV-2 in young and old adults

Grant number: CV004

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2020
  • Funder

    Wellcome Trust
  • Principle Investigator

    Pending
  • Research Location

    United Kingdom, Europe
  • Lead Research Institution

    Wellcome Sanger Institute
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    Gender

  • Study Subject

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Adults (18 and older)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Our key research questions are: How does the tissue immune response to the virus differ between young and old? How does the tissue immune response to the virus differ between older individuals who get mild disease versus severe disease? In those with severe fatal disease, does the nature of tissue immune responses across organs?