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A reagent-free viral detection platform

  • Funded by Fundação de Amparo à Pesquisa do Estado de São Paulo [São Paulo Research Foundation] (FAPESP)
  • Total publications:0 publications

Grant number: 2020/05497-4

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Key facts

  • Disease

    COVID-19, Dengue

  • Start & end year

    2020
    2020

  • Known Financial Commitments (USD)

    $71,863.56

  • Funder

    Fundação de Amparo à Pesquisa do Estado de São Paulo [São Paulo Research Foundation] (FAPESP)

  • Principal Investigator

    Paulo Roberto Bueno

  • Research Location

    Brazil

  • Lead Research Institution

    Universidade Estadual Paulista (Unesp)

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This is a proposal that involves a Joint Partnership (JP) between the University of São Paulo (USP) and the University of the State of São Paulo (UNESP) and will mainly focus on research on the development of portable electrochemical diagnostic devices for the detection viral infections of relevance to Brazil (flavivirus) and worldwide (SARS-Covid-2) using capacitive methods without reagents, already proven viable (in our thematic project) to detect DENV infections in serological samples from infected patients. Therefore, we are including in this proposal the use of this platform to diagnose COVID-19. The proposal provides for the use of a potentiostat the size of a pen-drive that can be attached to cell phones. The biggest challenge is to develop robust, reagent-free sensors for this type of device, which can effectively enable an electronic means of virus surveillance worldwide. The proposal is focused on overcoming the challenge of sensor manufacturing.