Return to homepagePandemic Pact

A rapid and inexpensive point of care diagnostic for SARS-CoV-2 infection

  • Funded by National Institutes of Health (NIH)
  • Total publications:0 publications

Grant number: 3R01EB028628-01S1

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2021

  • Known Financial Commitments (USD)

    $354,825

  • Funder

    National Institutes of Health (NIH)

  • Principal Investigator

    Matthew Bogyo

  • Research Location

    United States of America

  • Lead Research Institution

    Stanford University

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    Innovation

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Project Summary: The project outlines our plans to develop a rapid, point-of-care diagnostic test for the novel SARS-CoV-2 virus that can be used in resource-limited locations. The foundation of the project is a highly selective chemiluminescent reporter probe that produces light when activated by the major viral protease SARS-CoV-2 Mpro. This approach will enable rapid testing (<30 min) of easily obtained clinical samples (i.e., saliva) using a detector that has limited power needs and that can interface with standard smart phones to provide a diagnosis.