Tufts Clinical and Translational Science Institute (N3C Supplement)

PROJECT Summary: Tufts Clinical and Translational Science Institute (Tufts CTSI) is based on the conviction thatauthentic involvement of the entire spectrum of clinical and translational research (CTR) iscritical to fulfilling the promise of biomedical science for meeting the public's needs. Thisincludes not only from translation from bench to bedside (T1 translation), but also, crucially forhaving health impact, translation into effective clinical practice (T2), care delivery and publichealth (T3), and health policy (T4). Advances on all of these fronts is increasingly dependent onmaking effective use of scientific data from multiple domains.The COVID-19 global emergency presents both an immediate challenge and an opportunity toprogress on important data sharing aims emphasized by NIH. In response, NCATS and theCenters for Translational Science Award (CTSA) hubs, several HHS agencies, and otherpartnering organizations have committed to developing a next-generation repository for clinicaldata related to COVID-19, the National COVID Cohort Collaborative (N3C), as a means ofaccelerating global research into the disease and aiding the development of diagnostics,therapeutics, and effective vaccines. The N3C initiative's goal of improving the efficiency andaccessibility of analyses with clinical data is consistent with the primary informatics objectives ofTufts CTSI, which am to reduce barriers to the integration of healthcare and research byproviding innovative systems, data repositories, and analytical tools, and by enabling greaterexchange and collaboration through interoperability, standardization, and resource sharing. In-line with shared objectives, in this supplement we seek to contribute to the N3C initiative as adata provider and thought partner through the following specific aims: (1) continue to play animportant role providing tools and resources for N3C's analytics platform; and (2) ensure TuftsCTSI's Informatics Program has sufficient staff and technical resources to continue to provideCOVID-specific patient data from our hub to the N3C repository.