Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)

The Oregon Clinical and Translational Research Institute (OCTRI) has been accelerating research at OregonHealth & Science University since 2006. Its many highly functional programs assist investigators and traineesby providing diverse services. Here, we propose that OCTRI will transition to retain our strengths, but alsobecome a key hub in the national network, by focusing on five crosscutting aims. These align closely with thegoals of the Funding Opportunity Announcement, and the goals outlined by NCATS for the CTSA program inan ideal state. OCTRI's overall aims are to:Overall Aim 1: Catalyze Clinical and Translational Research.Overall Aim 2: Enhance Partnerships with Communities.Overall Aim 3: Foster and Support Scientific Collaboration.Overall Aim 4: Expand the Translational Workforce for the 21st Century.Overall Aim 5: Cultivate Innovation in Research.We have organized a highly functional leadership structure to enable us to meet these goals, and will seek theguidance of several advisory groups. We will catalyze research by developing and supporting new informaticsapproaches that both integrate the clinical care enterprise with the research enterprise and facilitate therecruitment of patients into clinical trials, locally and across the CTSA network. We will engage diversestakeholders in the translational research process, by partnering with OHSU investigators, communitycoalitions, and business enterprises. We will foster team science through local awards to trainees and toemerging investigators. We will partner with regional institutions to foster community-engaged research, toenhance the diversity of trainees, and to provide opportunities in biomedical research not available at otherinstitutions. We will train clinical and translational scientists and research staff for the next generation, byfocusing on the skills and attitudes necessary for research in the future. At all steps, we will measure outcomesand, when necessary, "turn the curve."