COVID-19 in university settings: Establishing an advanced research platform to inform control and mitigation strategies

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:15 publications

Grant number: MC_PC_20027

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2020
  • Known Financial Commitments (USD)

    $106,400
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    Professor Jonathan Ball
  • Research Location

    United Kingdom
  • Lead Research Institution

    University of Nottingham
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease transmission dynamics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Adults (18 and older)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Other

Abstract

Universities have been identified as potential high risk setting for SARS2 spread. This viewpoint is based on specific environmental and social factors - for example mass mobilisation, communal living and frequent social interactions - as well as biological determinants, such as asymptomatic or paucisymptomatic spread. However, the evidence-base is lacking. This project will provide an immediate and timely snapshot of SARS2 prevalence, its molecular epidemiology and seroprevalence in a large cohort (~6K) of hall-based students and associated frontline staff. It will also establish necessary modelling and behavioural research platforms to provide immediate and mid-term analysis of behaviours and social factors associated with infection and spread, as well as its mitigation, with a particular focus on social distancing. It will also utilise existing NIHR-supported activities focussing on the long-term consequences of COVID-19. This will have immediate impact on the national and international higher education community as well as longer-term benefits created through resulting multi-partner collaborative research. These studies will provide important insights into COVID-19, including its epidemiology, control and long-term health impacts.

Publicationslinked via Europe PMC

Optimization of the pseudoparticle system for standardized assessments of neutralizing antibodies against hepatitis C virus.

Hepatitis C subtyping assay failure in UK patients born in sub-Saharan Africa: Implications for global treatment and elimination.

Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study.

Simultaneous determination of HCV genotype and NS5B resistance associated substitutions using dried serum spots from São Paulo state, Brazil.

Mixed-methods process evaluation of a residence-based SARS-CoV-2 testing participation pilot on a UK university campus during the COVID-19 pandemic.

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013-2017, reveals distinct disease features and co-circulating genomic subtypes.

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding.

Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva.

The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout.