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COVID-19 Longitudinal Health and Wellbeing - National Core Study (LWH-NCS)

Grant number: MC_PC_20030

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2021

  • Known Financial Commitments (USD)

    $13,116,460

  • Funder

    UK Research and Innovation (UKRI)

  • Principal Investigator

    Professor Nishi Chaturvedi

  • Research Location

    United Kingdom

  • Lead Research Institution

    University College London

  • Research Priority Alignment

    N/A

  • Research Category

    Secondary impacts of disease, response & control measures

  • Research Subcategory

    Indirect health impacts

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The Longitudinal Health and Wellbeing National Core Study will improve understanding of C-19 infection risk factors, examine the physical and mental health consequences of asymptomatic to hospitalised cases, and assess the impact of population scale mitigation policy. We will unite distinct, but complementary, longitudinal studies already engaged in C-19 research, including UK representative population and hospitalised cohorts, household panel surveys, and national primary care registries. These will be enriched with health and administrative data linkage. Linkage, self-reporting and repeat serological assessment will allow greater precision in case assignment. This collective resource will be mined by a consortium of experienced analysts linked to these resources to provide rapid answers to existing and emerging priority research questions. For the first 6 months, these include short- and medium-term physical and mental health impacts of those who have had C-19 infection, risks of re-infection and role of risk factors, health effects of interruption to health care services, and the interplay between socioeconomic and health effects of viral suppression policies. Our outputs will include briefing notes as well as scientific reports in order to optimise policy influence.

Publicationslinked via Europe PMC

Last Updated:2 days ago

View all publications at Europe PMC

Impact of COVID-19 pandemic on rates of congenital heart disease procedures among children: prospective cohort analyses of 26 270 procedures in 17 860 children using CVD-COVID-UK consortium record linkage data.

Associations between different measures of SARS-CoV-2 infection status and subsequent economic inactivity: A pooled analysis of five longitudinal surveys linked to healthcare records.

Antibiotics for common infections in primary care before, during and after the COVID-19 pandemic: cohort study of extent of prescribing based on risks of infection-related hospital admissions.

COVID-19 risk by work-related factors: pooled analysis of individual linked data from 14 cohorts.

Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY.

Changes in opioid prescribing during the COVID-19 pandemic in England: an interrupted time-series analysis in the OpenSAFELY-TTP cohort.

Exploring Prior Antibiotic Exposure Characteristics for COVID-19 Hospital Admission Patients: OpenSAFELY

Cohort study of cardiovascular safety of different COVID-19 vaccination doses among 46 million adults in England.

Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients' records at source using OpenSAFELY.