Understanding novel viral host interactions that modulate innate immunity
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA143554
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Key facts
Disease
COVID-19Start & end year
20212024Known Financial Commitments (USD)
$573,184.5Funder
National Health and Medical Research Council (NHMRC)Research Location
AustraliaLead Research Institution
Charles Sturt UniversityResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnosticsResearch Subcategory
ImmunitySpecial Interest Tags
N/AStudy Type
Non-ClinicalClinical Trial Details
N/ABroad Policy Alignment
PendingAge Group
Not ApplicableVulnerable Population
Not applicableOccupations of Interest
Not applicable
Abstract
Lethal viruses such as coronaviruses (MERS, SARS-CoV-1, SARS-CoV-2), Dengue, Zika, Hendra, and Nipah have developed effective mechanisms of replication by dampening the host immune system. Here we will examine how viruses carry out these immune evasion functions, and test antiviral drugs that can prevent these effects in a highly specific manner. If this idea can be proved, it will provide great promise for the development of new antivirals whilst minimising the toxic effects to the cell.