CoV-2RBP Identification of proteins interacting with SARS-CoV-2 RNA during viral replication
- Funded by ANR
- Total publications:0 publications
Grant number: unknown
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Key facts
Disease
COVID-19start year
-99Known Financial Commitments (USD)
$0Funder
ANRPrincipal Investigator
Sarah Gallois- MontbrunResearch Location
FranceLead Research Institution
N/AResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen morphology, shedding & natural history
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
The CoV-2RBP project aims to identify viral and cellular factors that interact with SARS-CoV-2 RNAs and impact viral replication in cellular models of infection. They will mobilize cellular and molecular approaches to specifically label SARS-CoV-2 RNA, then isolate viral RNA-protein complexes, and identify interaction factors by mass spectrometry. The proteins of interest will then be validated for their interaction with SARS-CoV-2 RNA and their role in viral replication will be studied.