NiRCOVID Role of nicotinic receptors in the pathogenesis of COVID-19

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • start year

    -99
  • Known Financial Commitments (USD)

    $0
  • Funder

    ANR
  • Principal Investigator

    Uwe Maskos
  • Research Location

    France
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The NiRCOVID project will investigate the hypothesis that the nicotinic acetylcholine receptor (nAChR) is part of the infection process and pulmonary pathology, in particular with regard to the "cytokine storm" seen in severe cases. The project will explore potential treatment options using nicotinic receptor modulators in vitro and in vivo, in mice and human cultures.