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SensCOV Evaluation of the innate immune response in the SARSCOV2 / pulmonary organoid model: Role of TLRs

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    Elmostafa Bahraoui

  • Research Location

    France

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The SensCOV project will focus on characterizing, in a model of human pulmonary organoid infected by SARS-CoV-2, the molecular determinants involved in the pro-inflammatory response (including the intensity and kinetics of IFN-III production) and to understand the influence of age and gender on the inflammatory response induced by SARS-CoV-2.