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FIBROCO Involvement of circulating fibrocytes in the pathophysiogenesis and prognosis of severe lung disease in COVID-19

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    Bruno Crestani

  • Research Location

    France

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The FIBROCO project aims to better understand the physiopathogenesis of severe forms of Covid-19 and to establish the involvement of fibrocytes in the physiopathology and in the prognosis. A high level of circulating fibrocytes has been associated with a poor prognosis during acute respiratory distress syndrome (ARDS) and in idiopathic pulmonary fibrosis. Since Covid-19 pneumonia exhibits histological and inflammatory features similar to ARDS, the project will quantify circulating fibrocytes in patients with Covid and determine their prognostic value during Covid-19.