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PEDIMMCO Comparison of humoral effector immune responses and anti-SARS-CoV-2 memory T-cell immune responses in children with different levels of immunosuppression: a case-control study

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Known Financial Commitments (USD)

    $0

  • Funder

    ANR

  • Principal Investigator

    Guislaine Carcelain

  • Research Location

    France

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Children (1 year to 12 years)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The PEDIMMCO project plans to analyze humoral responses and anti-SARS-CoV-2 memory T cells in children with different levels / types of immunosuppression and in healthy controls followed in 4 university hospitals in Paris. It will determine and compare the quantity and quality of their humoral responses and memory T cells specific to SARS-CoV-2. This specific study of the pediatric population is particularly important for determining their potential for individual and collective protection, in particular with regard to immunocompromised children.