Synthetic reconstruction of an attenuated SARS-CoV-2 virus for vaccine development and a high-content inhibitor screen

Grant number: IPA/2020/000091

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Key facts

  • Disease

    COVID-19
  • Funder

    SERB India
  • Principal Investigator

    Dr. Anand Kumar Bachhawat
  • Research Location

    India
  • Lead Research Institution

    Indian Institute of Science Education and Research, Mohali
  • Research Priority Alignment

    N/A
  • Research Category

    Vaccines research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

New or repurposed antivirals against valid viral targets, viricidal coatings

Publicationslinked via Europe PMC

Identification of diphenylurea derivatives as novel endocytosis inhibitors that demonstrate broad-spectrum activity against SARS-CoV-2 and influenza A virus both in vitro and in vivo.