Structural and mechanistic studies to understand SARSCoV-2 ingress into human cells and its therapeutic intervention

Grant number: IPA/2020/000094

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Key facts

  • Disease

    COVID-19
  • Funder

    SERB India
  • Principal Investigator

    Dr. Jayanta Chatterjee
  • Research Location

    India
  • Lead Research Institution

    Indian Institute of Science Bangalore
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

New or repurposed antivirals against valid viral targets, viricidal coatings

Publicationslinked via Europe PMC

Drug targeting Nsp1-ribosomal complex shows antiviral activity against SARS-CoV-2.

A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein.