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CORONA - VirAn- Joint project: High-throughput multiplex bead assays; subproject 1: Multiplex beads for life science research and diagnostics and suspension bead assays for life sciences

  • Funded by Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)
  • Total publications:0 publications

Grant number: 03COV19A

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2023

  • Known Financial Commitments (USD)

    $513,651.06

  • Funder

    Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)

  • Principal Investigator

    Uwe Schedler

  • Research Location

    Germany

  • Lead Research Institution

    PolyAn Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The overall objective of the subproject is to synthesize, research and develop new multiplex beads to be used as basic and consumable materials in research to address the Covid-19 pandemic: a) Beads to be used in suspension bead assays b) Beads to be used in solid phase assays. In addition, new modular multiplex suspension bead assays will be developed and explored for use in research to address the Covid-19 pandemic. The subproject will explore the synthesis of microparticles via precipitation and emulsion polymerization, irreversible embedding of dyes into a polymeric bead matrix, targeted surface functionalization of dye-encoded microparticles, immobilization of biomolecules, especially antibodies onto the functional beads, and preparation, characterization of multiplex bead assays.