CORONA - VirAn- Joint project: High-throughput multiplex bead assays; subproject 3: Validation of multiplex bead assays.

The aim of the overall project is to establish modular bead-based assays for the study of viral infections. In this context, the aim of the subproject is to validate the developed bead assays for the analysis of murine and human samples after infection with SARS-CoV-2 or influenza. Furthermore, after adaptation and further development of the bead assays, it will be evaluated to what extent the assays can contribute to the identification of early predictors for the course of the disease as well as to the monitoring of a possible therapy. Samples from risk groups (mouse models) will also be used for this purpose. With the help of these experimental approaches, the subproject described here should make an essential contribution not only to validating the assays, but also to improving them. In addition, the results obtained should contribute to a better understanding, diagnosis and early treatment of infections with SARS-CoV-2 and the corresponding course of the disease.