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Novel Coronavirus Antiviral Drug Discovery Using High-Throughput Screening

  • Funded by Government of Ontario (Canada)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19

  • Known Financial Commitments (USD)

    $320,279.76

  • Funder

    Government of Ontario (Canada)

  • Principal Investigator

    Jean-Simon Diallo

  • Research Location

    Canada

  • Lead Research Institution

    Ottawa Hospital Research Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Using a novel bio-sensor that detects drugs that disrupt the attachment of coronaviruses to cells, this research will test approximately 1,200 approved drugs to better understand their potential to prevent viral infection in cells and their ability to block the interaction between COVID-19 and its receptor. A second phase of this study will attempt to identify novel antivirals from a small (>220,000) molecule library.